Core B: Translating Scientific Knowledge for Action to Protect Health and Environment


The Research Translation Core (RTC) will use effective methods to translate scientific findings and knowledge to those who can take actions to improve public health and protect the environment.  The RTC incorporates partnerships with government agencies and communication strategies for broad audiences.

  1. Addressing the greater susceptibilities of infants and children to environmental exposures —  Research by Berkeley SRP investigators and others demonstrates greater significance of exposures in early life to the development of disease.  Incorporating consideration of critical life stages and susceptibilities into public policy is a critical need.  We plan to collaborate with other researchers, US EPA, Cal EPA, and stakeholders to identify critical interventions that arise from the research to date, to translate findings for risk assessment, and to contribute to stable links between groups to amplify impact.
  2. Improving chemical testing and assessment methods —   EPA Administrator Jackson has made chemical safety one of her priority areas.  New findings and technologies could contribute to better methods to characterize hazards of chemicals at less cost, which would be valuable for assessment of existing Superfund sites and prevention of new ones.  The RTC plans to partner with US EPA and Cal EPA to translate new findings in this context and inform our broad audiences through existing networks.
  3. Reducing cumulative impacts of multiple stressors on communities — This is a key priority for US EPA and the Superfund program.  Most policy interventions for environmental factors focus on single pollutants.  We plan to collaborate with individuals at US EPA Region 9, the Office of Research and Development and the Office of Environmental Justice to contribute to translation of research for methods to consider cumulative impacts of multiple stressors in decisions at the regional and national level.
  4. Improving remediation for mercury — Mercury is a pervasive contaminant ranked third highest among those present at National Priority List sites.  Remediation of mercury at Superfund sites is thus a high priority but has had limited successes due to some of the unique properties and technological challenges of mercury.  We plan to identify ways to over come these challenges.
  5. The research strategy incorporates paths for technology transfer for each research project.  Investigators from Projects will also continue to participate in scientific advisory committees and expert panels and symposia organized by US EPA and other government agencies to transfer and transate scientific results.

The RTC will use best practice for communications with its partners, including collaborative project direction and interactions, and for its broad audiences, including use of social media tools and the development of tools for popular education.  The strategy reflects understanding of the mechanisms of uptake of scientific knowledge by government agencies and of the needs of broad audiences.

This is relevant because RTC engages the Project Scientists in order to help bring our research to application, policy initiatives, and public awareness.  The RTC partners with local, state, and federal agencies and NGOs to design and implement strategies to translate scientific findings and knowledge on cross-cutting topics in ways that are applicable to their needs.

Core Leadership

Amy Kyle, PhD, MPH

Associate Adjunct Professor and Research Scientist

Environmental Health Sciences,
School of Public Health
University of California, Berkeley

Core Update

This section is currently being updated.

Core Update Archive

Core News

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News Archive

Selected Publications


Su JG, Jerrett M, Morello-Frosch R, Jesdale BM, Kyle AD (2012) Inequalities in cumulative environmental burdens among three urbanized counties in California. Environ Int. Apr;40:79-87. PMID: 22280931. (PMC Journal – In Process). [PDF]


Johnson BE, Esser BK, Whyte DC, Ganguli PM, Austin CM, Hunt JR (2009) Mercury accumulation and attenuation at a rapidly forming delta with a point source of mining waste.Sci Total Environ. Sep 1; 407(18):5056-70. PMID: 19539980. PMCID: PMC2747606. [PDF]

Guyton KZ, Kyle AD, Aubrecht J, Cogliano VJ, Eastmond DA, Jackson M, Keshava N, Sandy MS, Sonawane B, Zhang L, Waters MD, Smith MT (2009) Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches. Mutat Res. Mar-Jun; 681(2-3):230-40. PMID: 19010444. [PDF]


Woodruff TJ, Zeise L, Axelrad DA, Guyton KZ, Janssen S, Miller M, Miller GG, Schwartz JM, Alexeeff G, Anderson H, Birnbaum L, Bois F, Cogliano VJ, Crofton K, Euling SY, Foster PM, Germolec DR, Gray E, Hattis DB, Kyle AD, Luebke RW, Luster MI, Portier C, Rice DC, Solomon G, Vandenberg J, Zoeller RT (2008) Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environ Health Perspect. Nov; 116(11):1568-75. PMID: 19057713. PMCID: PMC2592280. [PDF]


Chu W, Choy WK, Hunt JR (2005) Effects of nonaqueous phase liquids on the washing of soil in the presence of nonionic surfactants. Water Res. Jan-Feb; 39(2-3):340-8. PMID: 15644242. [PDF]