Publications

2022

Beene D, Collender P, Cardenas A, Harvey C, Huhmann L, Lin Y, Lewis J, Lolacono, Navas-Acien A, Nigra A, Steinmaus C, van Geen. A mass balance approach to evaluate arsenic intake and excretion in different populations. Environ Int. 2022 Jun 26;166:107371. Doi: 10.1016/j.envint.2022.107371. PMID: 35809487. PMCID: PMC9790973 (available on 2023-12-26)

Bozack* AK, Boileau* P, Hubbard AE, Sillé* FCM, Ferreccio C, Steinmaus CM, Smith MT, Cardenas A. The impact of prenatal and early-life arsenic exposure on epigenetic age acceleration among adults in Northern Chile. Environ Epigenet. 2022 Jun 1;8(1):dvac014. eCollection 2022. Doi: 10.1093/eep/dvac014. PMID: 35769198. PMCID: PMC9235373.

  • Data Availability: The datasets generated and/or analyzed during the current study are not publicly available due to participant confidentiality but are available from the corresponding author (andres.cardenas@stanford.edu) on reasonable request and upon Institutional Review Board review. The code used in data processing, analysis, and visualization of results is available at the study’s GitHub repository (https://github.com/annebozack/Chile_arsenic_EAA).

Duan* Y, Sedlak DL. An electrochemical advanced oxidation process for the treatment of urban stormwater. 2021 Dec. Water Research X. 13:100127. Doi: 10.1016/j.wroa.2021.100127. PMID: 34927040. PMCID: PMC8649961.

  • Data Availability: Data in paper and supporting information. Contact sedlak@berkeley.edu.

Germolec DR, Lebrec H, Anderson SE, Burleson GR, Cardenas A, Corsini E, Elmore SE, Kaplan BLF, Lawrence BP, Lehmann GM, Maier CC, McHale CM, Myers LP, Pallardy M, Rooney AA, Zeise L, Zhang L, Smith MT. Consensus on the Key Characteristics of Immunotoxic Agents as a Basis for Hazard Identification. Environmental Health Perspectives. 130(10):105001. doi: 10.1289/EHP10800.  PMID: 36201310. PMCID: PMC9536493

  • Data Availability: No data.

Jeon S, de Smith AJ, Li S, Chen M, Chan TF, Muskens IS, Morimoto LM, DeWan AT, Mancuso N, Metayer C, Ma X, Wiemels JL, Chiang CWK. Genome-wide trans-ethnic meta-analysis identifies novel susceptibility loci for childhood acute lymphoblastic leukemia (Letter). Leukemia 2021 Nov 8. doi: 10.1038/s41375-021-01465-1. PMID: 34750507. PMCID: PMC9075725.

Keren* R, Méheust R, Santini JM, Thomas A, West-Roberts J, Banfield JF, Alvarez-Cohen L. Global genomic analysis of microbial biotransformation of arsenic highlights the importance of arsenic methylation in environmental and human microbiomes. Computational and Structural Biotechnology Journal. 2022 20: 5590572. 2022. doi: 10.1016/j.csbj.2021.12.040. PMCID: PMC9582695.

  • Data Availability: Data in paper and SI (links below). Contact lisaac@ce.berkeley.edu.
  • Keren, Ray (2021): Supplementary information 1. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14912763.v3
  • Keren, Ray (2021): Supplementary table 2. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14912994.v2
  • Keren, Ray (2021): Supplementary table 1. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14912988.v1
  • Keren, Ray (2021): Supplementary table 4. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14913075.v1
  • Keren, Ray (2021): Supplementary table 5. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14955555.v1
  • Keren, Ray (2021): Supplementary table 6. figshare. Dataset. https://doi.org/10.6084/m9.figshare.14955558.v1
  • Keren, Ray (2021): Supplementary table 3. figshare. Dataset. https://doi.org/10.6084/m9.figshare.15177510.v1
  • Keren, Ray (2021): Supplementary information 2. figshare. Dataset. https://doi.org/10.6084/m9.figshare.15177543.v1

Li S, Sok P, Xu K, Muskens IS, Elliott N, Myint SS, Pandey P, Hansen HM, Morimoto LM, Kang AY, Metayer C, Ma X, Mueller BA, Roy A, Roberts I, Rabin KR, Brown AL, Lupo PJ, Wiemels JL, de Smith AJ. Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome. Blood Adv. 2022 Jul 26;6(14):4132-4136. doi: 10.1182/bloodadvances.2022007098. PMID: 35588500. PMCID: PMC9327551.

  • Data Availability: Data in paper and SI. Contact adam.desmith@med.usc.edu.

Nickels EM, Li S, Morimoto L, Kang AY, de Smith AJ, Metayer C, Wiemels JL. Periconceptional folate intake influences DNA methylation at birth based on dietary source in an analysis of pediatric acute lymphoblastic leukemia cases and controls. Am J Clin Nutr. 2022 Dec 19;116(6):1553-1564. doi: 10.1093/ajcn/nqac283. PubMed PMID: 36178055; PubMed Central PMCID: PMC9761733 (available on 23-09-30).

  • Data Availability Statement: Data described in the manuscript, code book, and analytic code will be made available upon reasonable request pending approval from authors. The data underlying this article are available in the article and in its online supplementary material. This study used biospecimens from the California Biobank Program, which prohibits uploading of genomic data (including genome-wide DNA-methylation) and/or sharing of individual level data obtained from these biospecimens under the statutory scheme of the California Health and Safety Code Sections 124980(j), 124991(b), (h), and 103850(a) and (d). Results of the EWAS analysis presented in this study are provided as a downloadable file for all subjects, Hispanic subjects only, and non-Hispanic white subjects (32).

Ocasio* D and Sedlak DL. Membrane-Assisted Electrochlorination for Zero-Chemical-Input Point-of-Use Drinking Water Disinfection. ACS EST Engg. 2022, 2(10:1933-1941. Doi: 10.1021/acsestengg.2c00116. PMCID: PMC10104438.

  • Data Availability: Data in paper and SI. Contact sedlak@berkeley.edu

Pace* C, Fencl A, Baehner L, Lukacs H, Cushing L, and Morello-Frosch R. The Drinking Water Tool: A Community-Driven Data Visualization Tool for Policy Implementation. Int. J. of Environmental Research and Public Health. 19(3):1419. 1/27/2022. Doi: 10.3390/ijerph19031419. PMID: 35162442.  PMCID: PMC8834844.

  • Data Availability: Data generated for this manuscript are available from the authors upon request. cpace@berkeley.edu

Pace* C, Balazs C, Bangia K, Depsky N, Renteria A, Morello-Frosch R, and Cushing LJ. Inequities in Drinking Water Quality Among Domestic Well Communities and Community Water Systems, California, 2011‒2019. Am. J. Public Health. 2022 Jan 1; 112(1):88-97. 10.2105/AJPH.2021.306561. PMID: 34936392. PMCID: PMC8713636.

  • Data Availability: Used secondary data sources. Contact cpace@berkeley.edu

Page ACS, Scholz SO, Keenan KN, Spradlin JN, Belcher* BP, Brittain SM, Tallarico JA, McKenna JM, Schirle M, Nomura DK, and Toste FD. Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design. Chem Sci. 2022. 13: 3851-6. DOI: 10.1039/D2SC00426G. PMID: 35432890. PMCID: PMC8966736.

  • Data Availability: The experimental data, including procedures and characterization data, have been uploaded as part of the Electronic supplementary information (ESI) available. See DOI: 10.1039/d2sc00426g.

Phillips* RV, Wei* L, Cardenas A, Hubbard AE, McHale CM, Vermeulen R, Wei H, Smith MT, Zhang L, Lan Q, Rothman R. Epigenome-Wide Association Studies of Occupational Exposure to Benzene and Formaldehyde. Epigenetics. Doi: 10.1080/15592294.2022.2115604 PMID: 36017556. PMCID: PMC9665125 (available on 2023-08-25).

Ramaprasad* ASE, Smith MT, McCoy* D, Hubbard AE, LaMerrill MA, Durkin KA. Predicting the binding of small molecules to nuclear receptors using machine learning. Briefings in Bioinformatics. 2022 Apr 5;bbac114. Doi: 10.1093/bib/bbac114. PMID: 35383362. PMCID: PMC9116378.

  • Data Availability: Data in paper and SI. Contact durkin@berkeley.edu
  •  ‘NR-ToxPred’ web server, to predict the binding of chemicals to the nine NRs using the best-performing models for each receptor, is freely accessible at http://nr-toxpred.cchem.berkeley.edu.

Tachachartvanich* P, Ettayapuram Ramaprasad* AS, Durkin KA, Furlow JD, Smith MT, La Merrill MA. In Vitro Characterization of the Endocrine Disrupting Effects of Per- and Poly-fluoroalkyl Substances (PFASs) on the Human Androgen Receptor. J. Hazardous Materials. 429: 128243. Doi: 10.1016/j.jhazmat.2022.128243. PMID: 35093747. PMCID: PMC9705075.

van der Laan* L, Cardenas A, Vermeulen R, Fadadu RP, Hubbard AE, Phillips* RV, Zhang L, Breeze C, Hu W, Wen C, Huang Y, Tang X, Smith MT, Rothman N, Lan Q. Epigenetic aging biomarkers and occupational exposure to benzene, trichloroethylene and formaldehyde. Environ Int. 2022 Jan;158:106871. doi:10.1016/j.envint.2021.106871. PMID: 34560324. PMCID: PMC9084243.

Wong JYY, Imani* P, Grigoryan H, Bassig BA, Dai Y, Hu W, Blechter B, Rahman ML, Ji BT, Duan H, Niu Y, Ye M, Jia X, Meng T, Bin P, Downward G, Meliefste K, Leng S, Fu W, Yang J, Ren D, Xu J, Zhou B, Hosgood HD, Vermeulen R, Zheng Y, Silverman DT, Rothman N, Rappaport SM, Lan Q. Exposure to diesel engine exhaust and alterations to the Cys34/Lys525 adductome of human serum albumin. Environ Toxicol Pharmacol. 2022 Sep 5;95:103966. doi: 10.1016/j.etap.2022.103966. PubMed PMID: 36067935; PMCID: PMC9757949 (available on 2023-10-01).

  • Data Availability: Data in paper and SI. Contact Jason.wong@nih.gov.

Xu K, Li S, Pandey P, Kang AY, Morimoto LM, Mancuso N, Ma X, Metayer C, Wiemels JL, de Smith AJ. Investigating DNA methylation as a mediator of genetic risk in childhood acute lymphoblastic Leukemia. Hum Mol Genet. 2022 Jun 18;ddac137. doi: 10.1093/hmg/ddac137.  PMID: 35717575. PMCID: PMC9616572 (available on 2023-06-18).

  • Data Availability: Data in paper and SI. Biospecimens and/or data used in this study were obtained from the California Biobank Program at the California Department of Public Health (CDPH), CBP request number 26, in accordance with Section 6555(b), 17 CCR. Contact adam.desmith@med.usc.edu

Xu K, Li S, Muskens IS, Elliott N, Myint SS, Pandey P, Hansen HM, Morimoto LM, Kang AY, Ma X, Metayer C, Mueller BA, Roberts I, Walsh KM, Horvath S, Wiemels JL, de Smith AJ. Accelerated epigenetic aging in newborns with Down syndrome. Aging Cell. 2022 Jul;21(7):e13652. doi: 10.1111/acel.13652. PMID: 35661546. PMCID: PMC9282838.

  • Data Availability: Data in paper and SI. Contact adam.desmith@med.usc.edu. This study used biospecimens from the California Biobank Program. Any uploading of genomic data (including genome‐wide DNA methylation data) and/or sharing of these biospecimens or individual data derived from these biospecimens has been determined to violate the statutory scheme of the California Health and Safety Code Sections 124980(j), 124991(b), (g), (h), and 103850 (a) and (d), which protect the confidential nature of biospecimens and individual data derived from biospecimens. Data for epigenetic clocks and available covariates in newborns with and without DS are included in the Supplemental Dataset.

2021

Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK. (2020) Discovery of a functional covalent ligand targeting an intrinsically disordered cysteine within MYC. Cell Chemical Biology 2021 Jan 21:28(1):4 13.e17. doi: 10.1016/j.chembiol.2020.09.001. PMID 32966806 PMCID: PMC7854864.

  • Data Availability: Data generated in this study will be made available upon reasonable request. Contact dnomura@berkeley.edu

Boileau* P, Hejazi* NS, Collica B, van der Laan MJ, and Dudoit S. cvCovEst: Cross-validated covariance matrix estimator selection and evaluation in R. Journal of Open Source Software. 2021. 6(63):3273. Doi: 10.21105/joss.03273. Software package.

Bozack* AK, Boileau* P, Wei* L, Hubbard AE, Sillé* FCM, Ferreccio C, Acevedo J, Hou L, Ilievski V, Steinmaus CM, Smith MT, Navas-Acien A, Gamble MV, Cardenas A. Exposure to arsenic at different life-stages and DNA methylation meta-analysis in buccal cells and leukocytes. Environ Health. 2021 Jul 9;20(1):79. doi:10.1186/s12940-021-00754-7. PMID: 34243768; PMCID: PMC8272372.

  • Data Availability: The datasets generated and/or analyzed during the current study are not publicly available due to participant confidentiality but are available from the corresponding author on reasonable request and upon institutional review board review. Code used in data processing and EWAS, and complete lists of differentially methylated positions (DMPs) and differentially variable positions (DVPs) (p < 0.05) in individual EWAS are available at the study’s Github repository (github.com/annebozack/SRP_arsenic_DNAm_metaanalysis). Data and code repository: https://osf.io/m76sx/? Supplemental Materials (and rights and permissions): https://ehjournal.biomedcentral.com/articles/10.1186/s12940-021-00754-7#Sec14

Chung MK, Rappaport SM, Wheelock CE, Nguyen VK, van der Meer TP, Miller GW, Vermeulen R, and Patel CJ. Utilizing a Biology-Driven Approach to Map the Exposome in Health and Disease: An Essential Investment to Drive the Next Generation of Environmental Discovery. Environ Health Perspect. 2021 Aug;129(8):85001. doi: https://doi.org/10.1289/EHP8327. PMID: 34435882. PMCID: PMC8388254.

  • Data Availability: No novel data or methods.

de la Rosa R*, Vazquez S*, Tachachartvanich P*, Daniels SI*, Sillé F*, Smith MT. Cell-Based Bioassay to Screen Environmental Chemicals and Human Serum for Total Glucocorticogenic Activity. Environmental Toxicol Chem. 2021 Jan; 40(1): 177-186. doi:10.1002/etc.4903. PMID: 33085113. PMCID: PMC7793542.

  • Data Availability: Data, associated metadata, and calculation tools are available from the corresponding author at rmd1025@berkeley.edu

Gushgari-Doyle* S, Oremland RS, Keren* R, Baesman SM, Akob DM, Banfield JF, and Alvarez-Cohen L. 2021. Acetylene-Fueled Trichloroethene Reductive Dechlorination in a Groundwater Enrichment Culture. mBio Jan-Feb; 12(1):e02724-20. doi: 10.1128/mBio.02724-20 PMID: 33531396 PMCID: PMC7858054

Iwashita H, Castillo E, Messina MS, Swanson RA, Chang CJ. A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2018513118. doi: 10.1073/pnas.2018513118. PMID: 33622793; PMCID: PMC7936376.

Lind L, Araujo JA, Barchowsky A, Belcher S, Berridge BR, Chiamvimonvat N, Chiu WA, Cogliano VJ, Elmore S, Farraj AK, Gomes AV, McHale CM, Meyer-Tamaki KB, Posnack NG, Vargas HM, Yang X, Zeise L, Zhou C, Smith MT. Key Characteristics of Cardiovascular Toxicants. Environ Health Perspect. 2021 Sep;129(9):95001. doi:10.1289/EHP9321. PMID: 34558968; PMCID: PMC8462506.

  • Data Availability: No datasets or software

Madrigal JM, Jones RR, Gunier RB, Whitehead TP, Reynolds P, Metayer C, Ward MH. Residential exposure to carbamate, organophosphate, and pyrethroid insecticides in house dust and risk of childhood acute lymphoblastic leukemia. Environ Res. 2021 Oct;201:111501. doi: 10.1016/j.envres.2021.111501. PMID: 34139223; PMCID: PMC8478811.

  • Data Availability: Data in paper and SI, request from jessica.madrigal@nih.gov

Marron EL, Van Buren* J, Cuthbertson* AA, Darby E, von Gunten U, and Sedlak DL. 2021. Reactions of a, ß-Unsaturated Carbonyls with Free Chlorine, Free Bromine, and Combined Chlorine. Environmental Science & Technology, 55(5):3305–3312. doi: 10.1021/acs.est.0c07660 PMID: 33565865 PMC9255599

Padula AM, Ma C, Huang H, Morello-Frosch R, Woodruff TJ, and Carmichael SL. 2021. Drinking water contaminants in California and hypertensive disorders in pregnancy. Environmental Epidemiology. Apr; 5(2):e149. doi: 10.1097/EE9.0000000000000149. PMID: 33870020 PMCID: PMC8043732

Rana* I, Rieswijk* L, Steinmaus C, and Zhang L. 2021. Formaldehyde and Brain Disorders: A Meta-Analysis and Bioinformatics Approach. Neurotoxicity Research. doi: 10.1007/s12640-020-00320-y. PMID: 33400181.  PMCID: PMC8102312.

  • Data Availability: All data generated or analyzed during this study are included in this published article and its supplementary information files. Contact luoping@berkeley.edu.

Rana* I, Dahlberg* S, Steinmaus C, Zhang L. Benzene exposure and non-Hodgkin lymphoma: a systematic review and meta-analysis of human studies. Lancet Planet Health. 2021 Sep;5(9):e633-e643. doi: 10.1016/S2542-5196(21)00149-2. PMID: 34450064. PMCID: PMC9109598.

  • Data Availability: This manuscript makes use of publicly available data from published studies; therefore, no original data are available for sharing. Contact luoping@berkeley.edu

Rider CV, McHale CM, Webster TF, Lowe L, Goodson III WH, La Merrill MA, Rice G, Zeise L, Zhang L, Smith MT. 2021. Using the Key Characteristics of Carcinogens to Develop Research on Chemical Mixtures and Cancer. Environmental Health Perspectives. Mar;129(3):35003. doi: 10.1289/EHP8525 PMID: 33784186 PMCID: PMC8009606.

  • Data Availability: No data or software

Rothman N, Vermeulen R, Zhang L, Hu W, Yin S, Rappaport SM, Smith MT, Jones DP, Rahman M, Lan Q, Walker DI. Metabolome-wide association study of occupational exposure to benzene. Carcinogenesis. 2021 Nov 12:bgab089. doi:10.1093/carcin/bgab089. PMID: 34606590. PMCID: PMC8598381.

  • Data Availability: Participant covariates and untargeted metabolomics data underlying this article are available on the Metabolomics Workbench (Study ID: ST001918; DOI: http://dx.doi.org/10.21228/M8F70B).

Rusyn I, Arzuaga X, Cattley RC, Corton JC, Ferguson SS, Godoy P, Guyton KZ, Kaplowitz N, Khetani SR, Roberts RA, Roth RA, Smith MT. Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity. Hepatology. 2021 Jun 9. doi: 10.1002/hep.31999. PMID: 34105804. PMCID: PMC8901129.

  • Data Availability: No data or software

Schildroth S, Osborne G, Smith AR, Yip C, Collins C, Smith MT, Sandy MS, Zhang L. Occupational exposure to antimony trioxide: a risk assessment. Occup Environ Med. 2021 May 13; oemed-2020-106980. doi: 10.1136/oemed-2020-106980. PMID: 33243757. PMCID: PMC8149478.

  • Data availability: Existing data used are publicly available from the National Toxicology Program Link.

Van Buren* J, Cuthbertson* AA, Ocasio* D, Sedlak L. Ubiquitous Production of Organosulfates During Treatment of Organic Contaminants with Sulfate Radicals. Environ Sci Technol Lett. 2021 Jul 13;8(7):574-580. doi: 10.1021/acs.estlett.1c00316. PMID: 34485590. PMCID: PMC8409489.

  • Data Availability: Data in paper and SI. Contact sedlak@berkeley.edu

Wheeler DC, Rustom S, Carli M, Whitehead TP, Ward MH, Metayer C. 2021. Assessment of Grouped Weighted Quantile Sum Regression for Modeling Chemical Mixtures and Cancer Risk. International Journal of Environmental Research and Public Health. 2021 Jan 9;18(2):504. doi: 10.3390/ijerph18020504 PMID: 33435473 PMCID: PMC7827322

  • Data Availability Statement: Request from cmetayer@berkeley.edu. The data are not publicly available due to privacy restrictions.

Wheeler DC, Rustom S, Carli M, Whitehead TP, Ward MH, Metayer C. Bayesian Group Index Regression for Modeling Chemical Mixtures and Cancer Risk. Int J Environ Res Public Health. 2021 Mar 27;18(7):3486. doi: 10.3390/ijerph18073486. PMID: 33801661; PMCID: PMC8037139.

  • Data Availability Statement: Request from cmetayer@berkeley.edu. The data are not publicly available due to privacy restrictions.

Whitehead TP, Wiemels JL, Zhou M, Kang AY, McCoy LS, Wang R, Fitch B, Petrick LM*, Yano Y*, Imani P*, Rappaport SM, Dahl GV, Kogan SC, Ma X, Metayer C. Cytokine Levels at Birth in Children Who Developed Acute Lymphoblastic Leukemia. Cancer Epidemiol Biomarkers Prev. 2021 Aug;30(8):1526-1535. doi: 10.1158/1055-9965.EPI-20-1704.  PMID: 34078642; PMCID: PMC8338848.

Xu K, Li S, Whitehead TP, Pandey P, Kang AY, Morimoto LM, Kogan SC, Metayer C, Wiemels JL, de Smith AJ. Epigenetic Biomarkers of Prenatal Tobacco Smoke Exposure Are Associated with Gene Deletions in Childhood Acute Lymphoblastic Leukemia. Cancer Epidemiol Biomarkers Prev. 2021 Aug;30(8):1517-1525. doi: 10.1158/1055-9965.EPI-21-0009.  PMID: 34020997; PMCID: PMC8338876.

  • Data Availability: Used existing datasets, data in paper or SI, request from adam.desmith@med.usc.edu

Zhang P, Carlsten C, Chaleckis R, Hanhineva K, Huang M, Isobe T, Koistinen VM, Meister I, Papazian S, Sdougkou K, Xie H, Martin JW, Rappaport SM, Tsugawa H, Walker DI, Woodruff TJ, Wright RO, Wheelock CE. Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective. Environ Sci Technol Lett. 2021 Oct 12;8(10):839-852. doi: 10.1021/acs.estlett.1c00648. PMID: 34660833; PMCID: PMC8515788.

  • Data Availability: No data.

Zhao Y*, Magaña L*, Cui H, Huang J, McHale CM, Yang X, Looney MR, Li R, Zhang L, 2020. Formaldehyde-induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose. Arch Tox. 2021 Feb; 95(2): 693–701. doi: 10.1007/s00204-020-02932-x. PMID: 33084937. PMCID: PMC7878325.

  • Data Availability: Data in paper. Contact luoping@berkeley.edu.

Zhao Y*, Wei L, Tagmount A, Loguinov A, Sobh A, Hubbard A, McHale CM, Chang CJ, Vulpe CD, Zhang L. 2021. Applying Genome-wide CRISPR to Identify Known and Novel Genes and Pathways that Modulate Formaldehyde Toxicity. Chemosphere. 269: 268701. doi: 10.1016/j.chemosphere.2020.128701  PMID: 33189395. PMCID: PMC7904579.

2020

Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK. 2020. Discovery of a functional covalent ligand targeting an intrinsically disordered cysteine within MYC. Cell Chemical Biology 28(1):4-13.e17. doi: 10.1016/j.chembiol.2020.09.001 PMID: 32966806 PMCID: PMC7854864 (available on 2022-01-21)

Bruemmer KJ, Crossley SWM, Chang CJ. 2020. Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond. Angew Chem Int Ed Engl. 59(33):13734-13762. doi: 10.1002/anie.201909690 PMID: 31605413 PMCID: PMC7665898

Castriota F, Rieswijk L, Dahlberg S, La Merrill MA, Steinmaus C, Smith MT, Wang JC. 2020. A State-of-the-Science Review of Arsenic’s Effects on Glucose Homeostasis in Experimental Models. Environ Health Perspect. Jan;128(1):16001. doi: 10.1289/EHP4517 PMID: 31898917 PMCID: PMC7015542

Castriota F, Zushin PH, Sanchez SS, Phillips RV, Hubbard A, Stahl A, Smith MT, Wang JC, La Merrill MA. 2020. Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice. Am J Physiol Endocrinol Metab. 318(5): E667-E677. PMID:32045263 PMCID: PMC7272725

de la Rosa R, Schlezinger JJ, Smith MT, Webster TF. 2020. Application of generalized concentration addition to predict mixture effects of glucocorticoid receptor ligands. Toxicol In Vitro. 69:104975. doi: 10.1016/j.tiv.2020.104975 PMID: 32858110  PMCID: PMC7594746 (available on 2021-12-01)

de la Rosa R, Vazquez S, Tachachartvanich P, Daniels SI, Sillé F, Smith MT. 2020. Cell-Based Bioassay to Screen Environmental Chemicals and Human Serum for Total Glucocorticogenic Activity. Environmental Toxicology. 40(1): 177-186. PMID: PMID: 33085113 PMCID: PMC7793542 (available on 2022-01-01)

Eick SM, Steinmaus C. 2020. Arsenic and Obesity: a Review of Causation and Interaction. Curr Environ Health Rep 7(3):343-351. doi: 10.1007/s40572-020-00288-z. PMID: 32766950 PMCID: PMC7891850 (available on 2021-09-01)

Elledge SK, Tran HL, Christian AH, Steri V, Hann B, Toste FD, Chang CJ, Wells JA. 2020. Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation. Proc Natl Acad Sci U S A. 117(11): 5733–5740.  doi: 10.1073/pnas.1920561117  PMID: 32123103 PMCID: PMC7084160

Ge J, Yang H, Lu X, Wang S, Zhao Y, Huang J, Xi J, Zhang L, Li R. 2020. Formaldehyde-induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose. Environ Int. Feb;95(2):693-701. doi: 10.1007/s00204-020-02932-x  PMID: 32861163. PMCID: PMC7878325 (available on 2022-02-01)

Guo H, Ahn S, Zhang L. 2020. Benzene-associated immunosuppression and chronic inflammation in humans: a systematic review. Occup Environ Med. Sep 16;oemed-2020-106517. doi: 10.1136/oemed-2020-106517 PMID: 32938756 PMCID: PMC7960562 (available on 2022-03-16)

Gushgari-Doyle S, Alvarez-Cohen L. 2020. Effects of arsenic on trichloroethene-dechlorination activities of Dehalococcoides mccartyi 195. Environ Sci Technol. 54(2):1276-1285. doi: 10.1021/acs.est.9b06527. PMID: 31913608. PMCID: PMC7792829

Isobe Y, Okumura M, White R, McGregor LM, Brittain SM, Jones MD, Liang X, White R, Forrester W, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK. 2020. Manumycin polyketides act as molecular glues between UBR7 and P53. Nature Chemical Biology doi: 10.1038/s41589-020-0557-2 PMID 3257277 PMCID: PMC7572527

La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT. 2020. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinology Jan;16(1):45-57. doi: 10.1038/s41574-019-0273-8  PMID: 31719706. PMCID: PMC6902641

Marron EL, Prasse C, Buren JV, Sedlak DL. 2020. Formation and Fate of Carbonyls in Potable Water Reuse Systems. Environ Sci Technol. 54(17):10895-10903. doi: 10.1021/acs.est.0c02793 PMID: 32833432 PMCID: PMC7755163 (available on 2021-09-01)

Nardone AL, Casey JA, Rudolph KE, Karasek D, Mujahid M, Morello-Frosch R. 2020. PLoS One 15(8):e0237241. doi: 10.1371/journal.pone.0237241 PMID: 32764800 PMCID: PMC7413562

Prasse C, von Gunten U, Sedlak DL. 2020. Chlorination of Phenols Revisited: Unexpected Formation of α,β-Unsaturated C4‐Dicarbonyl Ring Cleavage Products. Environmental Science & Technology. 52:195-204. doi: 10.1021/acs.est.9b04926  PMID: 31904937 PMCID: PMC7665061

Schildroth S, Osborne G, Smith AR, Yip C, Collins C, Smith MT, Sandy MS, Zhang L. 2020. Occupational exposure to antimony trioxide: a risk assessment. Occup Environ Med. Nov 26; oemed-2020-106980. doi: 10.1136/oemed-2020-106980. PMID: 33243757. In Process at NIHMS; NIHMSID: NIHMS 1655586

Sillé FCM, Karakitsios S, Kleensang A, Koehler K, Maertens A, Miller GW, Prasse C, Quiros-Alcala L, Ramachandran G, Rappaport SM, Rule AM, Sarigiannis D, Smirnova L, Hartung T. 2020. The exposome – a new approach for risk assessment. ALTEX 37(1):3-23. doi: 10.14573/altex.2001051. PMID: 31960937 PMCID not needed (Editorial –not peer-reviewed) Download Commentary

Smith MT, Guyton KZ, Kleinstreuer N, Borrel A, Cardenas A, Chiu WA, Felsher DW, Gibbons CF, Goodson WH, Houck KA, Kane A, La Merrill MA, Lebrec H, Lowe L, McHale CM, Minocherhomji S, Rieswijk L, Sandy MS, Sone H, Wang A, Zhang L, Zeise L, Fielden M. 2020. The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. Cancer Epidemiol Biomarkers Prev. 29(10):1887-1903. doi: 10.1158/1055-9965.EPI-19-1346 PMID: 32152214 PMCID: PMC7483401

Ueno K, Morstein J, Ofusa K, Naganos S, Suzuki-Sawano E, Minegishi S, Rezgui SP, Kitagishi H, Michel BW, Chang CJ, Horiuchi J, Saitoe M. 2020. Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release. J Neurosci. 40(18):3533-3548. PMID: 32253360 PMCID: PMC7189754

Van Buren J, Prasse C, Marron EL, Skeel B, Sedlak DL 2020. Ring-Cleavage Products Produced during the Initial Phase of Oxidative Treatment of Alkyl-Substituted Aromatic Compounds. Environ. Sci. Technol.  54(13):8352–8361. doi: 10.1523/JNEUROSCI.2378-19.2020 PMID: 32519538. PMCID: PMC7685676

Wheelock CE and Rappaport SM. 2020. The role of gene–environment interactions in lung disease: the urgent need for the exposome. Eur Respir J. 55(2). pii: 1902064. doi: 10.1183/13993003.02064-2019 PMID: 32029645 PMCID not needed (Editorial –not peer-reviewed)

Zhang L and Guo H. 2020. Biomarkers of COVID-19 and technologies to combat SARS-CoV-2. Advances in Biomarker Sciences and Technology. 2:1-23. doi: 10.1016/j.abst.2020.08.00 PMID: 33511330 PMCID: PMC7435336.

Zhao Y, Magaña L, Cui H, Huang J, McHale CM, Yang X, Looney MR, Li R, Zhang L, 2020 (published online Oct 21). Formaldehyde‑induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose. Arch Tox. 95: 693–701. doi: 10.1007/s00204-020-02932-x. PMID: 33084937 PMCID: PMC7878325

2019

Ahearn A. 2019. Key characteristics: a new approach to identifying potential toxicants, with Martyn Smith. The Researcher’s Perspective. 2019(1):doi:10.1289/EHP5776

Arzuaga X, Smith MT, Gibbons CF, Skakkelmek NE, Yost EE, Beverly BE, Hotchkiss AK, Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS. 2019. Proposed key characteristics of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health hazard assessments. Environmental Health Perspectives. 127(6):65001. doi:10.1289/ehp5045 PMID:31199676 PMCID: PMC6792367

Berdan C, Ho R, Lehtola H, To M, Hu X, Huffman T, Petri Y, Altobelli C, Demeulenaere S, Olzmann J, Maimone T, Nomura DK. 2019. Parthenolide covalently targets and inhibits focal adhesion kinase in breast cancer cells. Cell Chemical Biology. 26:1027. doi:10.1016/j.chembiol.2019.03.016 PMID:31080076 PMCID: PMC6756182

Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA, 2019. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575(7784):688-692. doi: 10.1038/s41586-019-1705-2 PMID: 31634900 PMCID: PMC6883167

Carlsson H, Rappaport SM, Tornqvist M. 2019. Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. High-Throughput. 8(1):6. doi:10.3390/ht8010006 PMID:30857166 PMCID: PMC6473736

Casey JA, Goin DE, Rudolph KE, Schwartz BS, Mercer D, Elser H, Eisen EA, Morello-Frosch R. 2019. Unconventional natural gas development and adverse birth outcomes in Pennsylvania: The potential mediating role of antenatal anxiety and depression. Environmental Research Oct;177:108598. doi: 10.1016/j.envres.2019.108598 PMID: 31357155. PMCID: PMC6726131

Christian A, Jia S, Cao W, Zhang P, Meza A, Sigman M, Chang C, Toste FD. 2019. A physical organic approach to tuning reagents for selective and stable methionine bioconjugation. Journal of the American Chemical Society. 141:12657-12662. doi:10.1021/jacs.9b04744 PMID:31361488 PMCID: PMC6781863

Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK, 2019. Covalent targeting of the vacuolar H +-ATPase activates autophagy via mTORC1 inhibition. Nat Chem Biol. 15(8):776-785. doi: 10.1038/s41589-019-0308-4 PMID: 31285595. PMCID: PMC6641988.

de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antillón F, Girón V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL. 2019. Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. Leukemia. Nov;33(11):2746-2751. doi: 10.1038/s41375-019-0514-9 PMID: 31296947 PMCID: PMC6858994

Eick SM, Ferreccio Readi C, Acevedo J, Castriota F, Cordero JF, Roh T, Smith AH, Smith MT, Steinmaus CM. 2019. Socioeconomic status and the association between arsenic exposure and type 2 diabetes. Environmental Research. 172:578-585. doi:10.1016/j.envres.2019.03.013 PMID:30875511 PMCID: PMC7003534

Gerlovina I and Hubbard AE. 2019. Computer Algebra and Algorithms for Unbiased Moment Estimation of Arbitrary Order. Cogent Mathematics and Statistics. 6(1):1701917. doi: 10.1080/25742558.2019.1701917 PMID: 33043279 PMCID: PMC7546107

Grigoryan H, Schiffman C, Gunter MJ, Naccarati A, Polidoro S, Dagnino S, Dudoit S, Vineis P, and Rappaport SM. 2019. Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology. Cancer Research. 79(23): p. 6024-603. doi: 10.1158/0008-5472.CAN-19-1529 PMID: 31641032 PMCID: PMC6891211

Jia S, He D, Chang C. 2019. Bioinspired thiophosphorodichloridate reagents for chemoselective histidine bioconjugation. Journal of the American Chemical Society. 141(18):7294-7301. doi:10.1021/jacs.8b11912 PMID:31017395 PMCID: PMC6996876

La Merrill MA, Johnson CL, Smith MT, Kandula NR, Macherone A, Pennell KD, Kanaya AM. 2019. Exposure to Persistent Organic Pollutants (POPs) and Their Relationship to Hepatic Fat and Insulin Insensitivity among Asian Indian Immigrants in the United States. Environmental Science and Technology. Dec 3;53(23):13906-13918 doi: 10.1021/acs.est.9b03373. PMID:31746186. PMCID: PMC6996970

Lee KM, Bassig BA, Zhang L, Vermeulen R, Hu W, Wong JJ, Wen C, Huang Y, Purdue MP, Ji B, Li L, Tang X, Rothman N, Smith MT, Lan Q. 2019. Association between occupational exposure to trichloroethylene and serum levels of microRNAs: a cross-sectional molecular epidemiology study in China. International Archives of Occupational and Environmental Health. Nov; 92(8): 1077–1085. doi:10.1007/s00420-019-01448-x PMID:31161417 PMCID: PMC6953905

Lee KM, Zhang L, Vermeulen R, Hu W, Bassig BA, Wong JJ, Qiu C, Purdue MP, Wen C, Walker DI, Jones DP, Li L, Huang Y, Rothman N, Smith MT, Lan Q. 2019. Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards. Occupational and Environmental Medicine. 76(6):376-381. doi:10.1136/oemed-2018-105583 PMID:30971425 PMCID: PMC6953904

Luderer U, Eskenazi B, Hauser R, Korach KS, McHale CM, Moran-Messen FM, Rieswijk L, Solomon G, Udagawa O, Zhang L, Zlatnik M, Zeise L, Smith MT. 2019. Proposed key characteristics of female reproductive toxicants as an approach for organizing and evaluating mechanistic data in hazard assessment. Environmental Health Perspectives. 127(7):75001. doi:10.1289/ehp4971 PMID:31322437 PMCID: PMC6791466

Mao X, Stenuit B, Tremblay J, Yu K, Tringe SG, Alvarez-Cohen L. 2019. Structural dynamics and transcriptomic analysis of Dehalococcoides mccartyi within a TCE-Dechlorinating community in a completely mixed flow reactor. Water Res. Jul 1;158:146-156. doi: 10.1016/j.watres.2019.04.038 PMID: 31035191 PMCID: PMC7053656

Pace, C., Balazs, C., Cushing, L., Morello-Frosch, R. 2019. Locating domestic well communities in California: A Methodological Overview. Domestic Well Layer (version 1.0). Prepared by the Water Equity Science Shop, UC Berkeley, CA. Download White Paper

Phillips RV, Rieswijk L, Hubbard AE, Vermeulen R, Zhang J, Hu W, Li L, Bassig BA, Wong JJ, Reiss B, Huang Y, Wen C, Purdue MP, Tang X, Zhang L, Smith MT, Rothman N, Lan Q. 2019. Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer. Epigenetics. doi:10.1080/15592294.2019.1633866 PMID:31241004 PMCID: PMC6773405

Schiffman, C, Petrick L, Perttula K, Yano Y, Carlsson H, Whitehead T, Metayer C,  Hayes J, Rappaport SM, and Dudoit S. 2019. Filtering procedures for untargeted LC-MS metabolomics data. BMC Bioinformatics. 20(1): p. 334. doi: 10.1186/s12859-019-2871-9 PMID: 31200644 PMCID: PMC6570933

Sobh A, Loguinov AV, Stornetta A, Balbo S, Tagmount A, Zhang L, Vulpe CD. 2019. Genome-wide CRISPR screening identifies the tumor suppressor candidate OVCA2 as a determinant of tolerance to acetaldehyde. Toxicological Sciences. 169:235-245. doi:10.1093/toxsci/kfz037 PMID:31059574 PMCID:PMC6484886

Sobh A, Loguinov AV, Yazici GN, Zeidan RS, Tagmount A, Hejazi NS, Hubbard AE, Zhang L, Vulpe CD. 2019. Functional profiling identifies determinants of arsenic trioxide cellular toxicity. Toxicological Sciences. 169:108-121. doi:10.1093/toxsci/kfz024 PMID:30815697 PMCID:PMC6484884

Spradlin JN, Xirui H, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK, 2019. Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. Nat Chem Biol. PMID: 31209351. PMCID: PMC6592714

Su TA, Bruemmer KJ, Chang CJ, 2019. Caged luciferins for bioluminescent activity-based sensing. Curr Opin Biotechnol. 60:198-204. doi: 10.1016/j.copbio.2019.05.002 PMID: 31200275 PMCID: PMC6891152

Yang, Duan Y, Wang J, Wang H, Liu H, Sedlak DL. 2019. Impact of Peroxymonocarbonate on the Transformation of Organic Contaminants during Hydrogen Peroxide in Situ Chemical Oxidation. Environ Sci Technol. Letters. doi: doi/full/10.1021/acs.estlett.9b00682 PMID: 33163542 PMCID: PMC7643861

Yano, Y, Schiffman C, Grigoryan H, Hayes J, Edmands W, Petrick L, Whitehead T, Metayer C, Dudoit S, and Rappaport SM. 2019. Untargeted adductomics of newborn dried blood spots identifies modifications to human serum albumin associated with childhood leukemia. Leukemia Research. 88: p. 106268. doi: 10.1016/j.leukres.2019.106268 PMID: 31760269 PMCID: PMC6937378

2018

Barazesh JM, Prasse C, Wenk J, Berg S, Remucal CK, Sedlak DL. 2018. Trace element removal in distributed drinking water treatment systems by cathodic H2O2 production and UV photolysis. Environmental Science & Technology. 52:195-204. doi:10.1021/acs.est.7b04396 PMID:29240414 PMCID: PMC5772888

Bruton TA, Sedlak DL. 2018. Treatment of perfluoroalkyl acids by heat-activated persulfate under conditions representative of in situ chemical oxidation. Chemosphere. 206:457-464. doi:10.1016/j.chemosphere.2018.04.128 PMID:29775938 PMCID:PMC6347461

Castriota F, Acevedo J, Ferreccio Readi C, Smith AH, Liaw J, Smith MT, Steinmaus CM. 2018. Obesity and increased susceptibility to arsenic-related type 2 diabetes in Northern Chile. Environmental Research. 167:248-254. doi:10.1016/j.envres.2018.07.022 PMID:30059859 PMCID:PMC6277209

Chang C, Chung CY, Timblin GA, Saijo K. 2018. Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining. Journal of the American Chemical Society. 140:6109-6121. doi:10.1021/jacs.8b02279 PMID:29722974 PMCID:PMC6069982

Counihan JL, Wiggenhorn AL, Anderson KE, Nomura DK. 2018. Chemoproteomics-enabled covalent ligand screening reveals ALDH3A1 as a lung cancer therapy target. ACS Chemical Biology. 13(8):1970-1977. doi:10.1021/acschembio.8b00381 PMID:30004670 PMCID:PMC6389507

Daniels SI, Chambers JC, Sanchez SS, La Merrill MA, Hubbard AE, Macherone A, McMullin M, Zhang L, Elliott P, Smith MT, Kooner J. 2018. Elevated Levels of Organochlorine Pesticides in South Asian Immigrants are Associated with an Increased Risk of Diabetes. Journal of the Endocrine Society. 2(8):832-841. doi: 10.1021/acs.est.7b04832. PMID: 30019022 PMCID: PMC6041775

Edmands WM, Hayes J, Rappaport SM. 2018. SimExTargId: a comprehensive package for real-time LC-MS data acquisition and analysis. Bioinformatics. 34(20):3589-3590. doi:10.1093/bioinformatics/bty218 PMID:29790936 PMCID:PMC6184452

Grigoryan H, Edmands WM, Lan Q, Carlsson H, Vermeulen R, Zhang L, Yin S, Li G, Smith MT, Rothman N, Rappaport SM. 2018. Adductomic signatures of benzene exposure provide insights into cancer induction. Carcinogenesis. 39:661-668. doi:10.1093/carcin/bgy042 PMID:29538615 PMCID:PMC5932554

Guo J, Zhao Y, Jiang X, Li R, Xie H, Ge L, Xie B, Yang X, Zhang L. 2018. Exposure to formaldehyde perturbs the mouse gut microbiome. Genes. 9:18. doi:10.3390/genes9040192 PMID:29614050 PMCID:PMC5924534

Guyton KZ, Rieswijk L, Wang A, Chiu WA, Smith MT. Key Characteristics Approach to Carcinogenic Hazard Identification. Chem Res Toxicol. 2018 Dec 6. doi: 10.1021/acs.chemrestox.8b00321. [Epub ahead of print Dec 6, 2018]. PMID: 30521319. Free Access to Paper

Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis. 39:614-622. doi:10.1093/carcin/bgy031 PMID:29562322 PMCID:PMC5888955

Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Re: Application of the key characteristics of carcinogens in cancer hazard evaluation : response to Goodman, Lynch and Rhomberg. Carcinogenesis. 39:1091-1093. doi:10.1093/carcin/bgy082 PMID:29982359 PMCID:PMC6067125

Ju C, Bibaut A, van der Laan MJ. 2018. The relative performance of ensemble methods with deep convolutional neural networks for image classification. Journal of Applied Statistics. 45(15):2800-2818. doi:10.1080/02664763.2018.1441383 PMID: 31631918 PMCID: PMC6800663

Lavy A, Keren R, Yu K, Thomas BC, Alvarez-Cohen L, Banfield JF, Ilan M. 2018. A novel Chromatiales bacterium is a potential sulfide oxidizer in multiple orders of marine sponges. Environmental Microbiology. 20:800-814. doi:10.1111/1462-2920.14013 PMID:29194919 PMCID:PMC5812793

McHale CM, Osborne G, Morello-Frosch R, Salmon AG, Sandy MS, Solomon G, Zhang L, Smith MT, Zeise L. 2018. Assessing health risks from multiple environmental stressors: moving from G x E to I x E. Mutation Research. Reviews in Mutation Research. 775:11-20. doi:10.1016/j.mrrev.2017.11.003 PMID:29555026 PMCID:PMC5863617

Perttula K, Schiffman C, Edmands WM, Petrick L, Grigoryan H, Cai X, Gunter MJ, Naccarati A, Polidoro S, Dudoit S, Vineis P, Rappaport SM. 2018. Untargeted lipidomic features associated with colorectal cancer in a prospective cohort. BMC Cancer. 18:996. doi:10.1186/s12885-018-4894-4 PMID:30340609 PMCID:PMC6194742

Perttula K, Schiffman C, Edmands WM, Petrick L, Grigoryan H, Cai X, Gunter MJ, Naccarati A, Polidoro S, Dudoit S, Vineis P, Rappaport SM. 2018. Untargeted lipidomic features associated with colorectal cancer in a prospective cohort. BMC Cancer. 18:996. doi:10.1186/s12885-018-4894-4 PMID:30340609 PMCID:PMC6194742

Prasse C, Ford B, Nomura DK, Sedlak DL. 2018. Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. Proceedings of the National Academy of Sciences of the United States of America. 115:2311-2316. doi: 10.1073/pnas.1715821115 PMID: 29463747 PMCID: PMC5877969

Rappaport SM. 2018. Redefining environmental exposure for disease etiology. NPJ Systems Biology and Applications. 4(30):doi:10.1038/s41540-018-0065-0 PMID:30181901 PMCID:PMC6119193

Roh T, Steinmaus C, Marshall G, Ferreccio C, Liaw J, Smith AH. 2018. Age at exposure to arsenic in water and increased mortality 30-40 years after exposure cessation. American Journal of Hematology. 187(11):2297-2305. doi: 10.1093/aje/kwy159. PMID: 30084889. PMCID: PMC6211243

Rothman N, Zhang L, Smith MT, Vermeulen R, Lan Q. 2018. Formaldehyde, hematotoxicity, and chromosomal changes-response. Cancer Epidemiology, Biomarkers & Prevention. 27:120-121. doi:10.1158/1055-9965.epi-17-0804 PMID:29311167 PMCID: PMC6980366

Schiffman C, McHale CM, Hubbard AE, Zhang L, Thomas R, Vermeulen R, Li G, Shen M, Rappaport SM, Yin S, Lan Q, Smith MT, Rothman N. 2018. Identification of gene expression predictors of occupational benzene exposure. PloS One. 13(10):e0205427. doi:10.1371/journal.pone.0205427 PMID:30300410 PMCID: PMC6177191

Smith AH, Marshall G, Roh T, Ferreccio C, Liaw J, Steinmaus C. Lung, Bladder, and Kidney Cancer Mortality 40 Years After Arsenic Exposure Reduction. Journal of the National Cancer Institute. 110(3):241-249. DOI:10.1093/jnci/djx201 PMID: 29069505. PMCID:PMC6059241.

Su TA, Shihadih DS, Cao W, Detomasi TC, Heffern MC, Jia S, Stahl A, Chang C. 2018. A modular lonophore platform for liver-directed copper supplementation in cells and animals. Journal of the American Chemical Society. 140(42):13764-13774. doi:10.1021/jacs.8b08014 PMID:30351140 PMCID: PMC6465169

Tachachartvanich P, Sangsuwan R, Ruiz HS, Sanchez SS, Durkin KA, Zhang L, Smith MT. 2018. Assessment of the endocrine-disrupting effects of trichloroethylene and its metabolites using in vitro and in silico approaches. Environmental Science & Technology. 52(3):1542-1550. doi:10.1021/acs.est.7b04832 PMID:29294279 PMCID:PMC6290898

Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X. 2018. GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Nature Communications. 9:8. doi:10.1038/s41467-017-02596-9 PMID:29348612 PMCID:PMC5773513

Yi S, Harding-Marjanovic KC, Houtz EF, Gao Y, Lawrence JE, Nichiporuk RV, Iavarone A, Zhuang W, Field JA, Sedlak DL, Alvarez-Cohen L. 2018. Biotransformation of AFFF component 6:2 fluorotelomer thioether amido sulfonate generates 6:2 fluorotelomer thioether carboxylate under sulfate-reducing conditions. Environmental Science & Technology Letters. 5:283-288. doi:10.1021/acs.estlett.8b00148 PMID:30705920 PMCID:PMC6350918

2017

Bessonneau V, Pawliszyn J, Rappaport SM. 2017. The saliva exposome for monitoring of individuals’ health trajectories. Environmental Health Perspectives. 125:10. doi:10.1289/ehp1011 PMID:28743678 PMCID: PMC5801473

Bruton TA, Sedlak DL. 2017. Treatment of aqueous film-forming foam by heat-activated persulfate under conditions representative of in situ chemical oxidation. Environmental Science & Technology. 51:13878-13885. doi:10.1021/acs.est.7b03969 PMID:29164864 PMCID:PMC5719469

Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang C, Vazquez A, Patel KJ. 2017. Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature. 548:549-554. doi:10.1038/nature23481 PMID:28813411 PMCID:PMC5714256

De la Rosa R, Steinmaus C, Akers NK, Conde L, Ferreccio C, Kalman D, Zhang KR, Skibola CF, Smith AH, Zhang L, Smith MT.Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population. Environ Mol Mutagen. 2017 Jul;58(6):411-422. doi: 10.1002/em.22104. Epub 2017 Jun 22. PMID:28640505  PMCID:PMC5515250

Hall EM, Acevedo J, Lopez FG, Cortes S, Ferreccio Readi C, Smith AH, Steinmaus CM. 2017. Hypertension among adults exposed to drinking water arsenic in Northern Chile. Environmental Research. 153:99-105. doi:10.1016/j.envres.2016.11.016 PMID:27918984 PMCID:PMC5534354

Mao X, Polasko A, Alvarez-Cohen L. 2017. Effects of sulfate reduction on trichloroethene dechlorination by Dehalococcoides-containing microbial communities. Applied and Environmental Microbiology. 83(8):e03384-16. doi:10.1128/AEM.03384-16 PMID:28159790 PMCID:PMC5377507

Men Y, Yu K, Baelum J, Gao Y, Tremblay J, Prestat E, Stenuit B, Tringe SG, Jansson J, Zhang T, Alvarez-Cohen L. 2017. Metagenomic and metatranscriptomic analyses reveal the structure and dynamics of a dechlorinating community containing Dehalococcoides mccartyi and corrinoid-providing microorganisms under cobalamin-limited conditions. Applied and Environmental Microbiology. 83(8):e03508-16. doi:10.1128/aem.03508-16 PMID:28188205 PMCID:PMC5377501

Nardone A, Ferreccio Readi C, Acevedo J, Enanoria W, Blair A, Smith AH, Balmes JR, Steinmaus CM. 2017. The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile. Environmental Research. 158:710-719. doi:10.1016/j.envres.2017.06.024 PMID:28738299 PMCID:PMC5603214

Petrick L, Edmands WM, Schiffman C, Grigoryan H, Perttula K, Yano Y, Dudoit S, Whitehead TP, Metayer C, Rappaport SM. 2017. An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies. Metabolomics 13:27. doi:10.1007/s11306-016-1153-z PMID:29706849 PMCID:PMC5918689